Characterization of Conformation of Therapeutic Antibody Aggregation with Optimized Hydrogen/Deuterium Exchange Mass Spectrometer
نویسندگان
چکیده
Herceptin and its pH stressed samples were quantified by measuring UV 280 absorption. Figure 4 is the overlay absorption spectra of four samples. Aggregations around 25% for pH 0.5, 6% for pH 1.5 and 0% for pH 2.5 were observed. Figure 3. a). Flexible three valve configuration for carrying out different experimental tasks simultaneously in the cooling chamber, b). NCS-3500RS with binary rapid separation micro flow pump with ternary loading pump
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